Endocrine Abstracts

Introduction: Accurately discern malignant from benign nodules sometimes represents a real challenge. Fine needle aspiration (FNA) biopsy, ultrasound and The Bethesda System for Reporting Thyroid Cytopathology (BSRTC) allow for accurate diagnosis in 60–80% of all nodules. However, 10–20% of thyroid FNAs yield an indeterminate cytology (BSRTC III and IV categories). The real malignancy rate of BSRTC III category is difficult to ascertain because histopathological anal...

Introduction: Thyroid nodules (TN) may display somatic RAS mutations, that, however, lack of diagnostic value. In our experience, somatic RAS mutation evaluation could be useful since it has a very high negative predictive value. In the past, somatic RAS mutation had been associated with a good prognosis in thyroid cancer.Objective: This study aims to evaluate whether somatic RAS mutation may associate with TN differential growth pattern.<p class="ab...